Microbiology R&D Scientist – Antimicrobial Materials
Location: Seattle, WA
Type: Full-time
About Singletto
Singletto is building Oxafence, an antimicrobial materials platform designed for real-world infection prevention and military protection. We partner with manufacturers of PPE, uniforms, bandages, tissues, and other everyday products to translate applied microbiology and chemistry into evidence-backed medical and protective materials. Our work emphasizes scientific rigor, regulatory discipline, and practical adoption in healthcare, military, and consumer settings. Singletto is a venture-backed startup and operates at the intersection of translational science, product development, and early commercial scale.
Role Summary
Singletto is developing antimicrobial materials and infection-control products that must perform under real-world conditions and stand up to regulatory and commercial scrutiny. We are seeking an experienced Microbiology R&D Scientist to join our team to bring rigorous experimental judgment that directly shapes our product performance, claim defensibility, and real-world clinical impact. The role will be on-site in our BSL-2 lab in Fremont (Seattle), Washington.
You will own the design, execution, interpretation, and documentation of in-house antimicrobial efficacy testing. The emphasis is on experimental thinking and decision-ready data, including knowing when to design exploratory assays and when to consistently and rigorously execute standard protocols (e.g., ISO, AATCC) to generate verifiable, decision-driving results.
This work supports programs including the Oxafence ProGear Mask, a disposable medical mask incorporating Oxafence and based on light-activated photosensitizers such as Methylene Blue. Our approach is evidence-backed and must be communicated with scientific precision.
Direct experience with formal antimicrobial standards (e.g., AATCC, ISO, ASTM, etc.) is valuable but not required if you have strong experimental background in bacterial or other microbial assays used for real-world decisions.
What You'll Do
Experimental Design
Design microbial assays to evaluate:
antimicrobial materials, surfaces, coatings, and substrates
performance under real-world conditions (e.g., light exposure, time, wear, contamination, etc.)
Apply, adapt, or extend existing methods, including:
standard antimicrobial tests (AATCC 100, ISO 18184, etc.) where appropriate
internally develop or modified assays
Know when a method is:
sufficient
misleading
or needs controlled modification
Execution & Iteration
Run hands-on BSL-2 level antimicrobial experiments involving:
bacteria (required)
viruses (if appropriately supported and required)
fungi (as needed)
Execute repeatable, quantitatively sound experiments including:
Growth and preparation of tested microbes
Conducts CFU counts
Completes time-kill studies (log reductions)
Analyzes and interpret assays
Iterate intelligently: test → interpret → refine → retest
Maintain a sterile, clean, and organized lab environment
Documentation & Interpretation
Maintain clean, traceable lab notebooks (digital/written) including photo documentation
Produce written technical summaries that explain:
what was done
why it was done
what the data mean
what decisions or next experiments it supports
Compare:
New findings to prior in-house, and external partner lab results
to existing related and analogous scientific literature
Proactively flag:
possible artifacts of experimentation or quantitative analysis
necessary controls to account for methodologies used
false positives / false negatives
uncertainty that affects decisions
Inform R&D and Strategy
Translate experimental results into:
key learnings and limitations
prioritized next experiments where appropriate
formulation, material, or application changes that could improve efficacy
exposure parameters (e.g., light conditions, duration, timepoints)
Document results and interpretations for R&D and cross-functional discussions, producing:
clear, well-structured technical written summaries
accurate and complete data tables and Excel spreadsheets with appropriate controls
appropriately labeled graphs that support interpretation
Work closely with chemistry, materials, and leadership to align experimental findings with product and strategy decisions
Help build and organize a growing body of completed studies and results that compound over time and support future regulatory pathways
What We’re Looking For
Must-Haves
Hands-on microbiology experience:
BS in related field + 3 or more years of relevant lab work
MS in related field + 2 or more years of relevant lab work
Direct design and execution of bacterial or other microbial assays, including:
assay design or modification
quantitative readouts via data tables and scientific charts (CFU, kill curves stated as log reduction, etc.)
Strong experimental judgment:
can explain results clearly in writing and oral presentation without jargon
comfortable saying “I don’t trust this result yet”
thinks in cause-and-effect
Demonstrated judgment in balancing scientific rigor with execution speed, including knowing when additional documentation or investigation meaningfully improves decisions, and when it does not.
Experience working in applied, industry, or decision-driven lab environments
High documentation discipline and comfort working in regulated or quality-adjacent contexts
Valuable (But Not Required)
• Formal antimicrobial efficacy testing (AATCC 100, ISO 18184)
• Surface, materials, textile, or coatings microbiology
• Antiviral or disinfectant testing
• Photodynamic or light-activated systems
• FDA or EPA regulated environments
• In vitro immune testing experience
Why Join Singletto?
Be part of introducing OxafenceTM as the next iconic technology brand – like Gore-Tex or Kleenex.
Shape the messaging that helps save and improve lives, tackle the antimicrobial resistance crisis, protect military personnel, and offer better antimicrobial alternatives for the planet.
Collaborate closely with executive leadership in a fast-moving, high-impact environment.
To Apply
Send your resume and 1–2 relevant writing samples (e.g. research papers, published studies, scientific graphs and charts) to careers@singletto.com. Include a short note explaining why this role is a good fit and how your background aligns.